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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c75e18fd0477d44258e3f71f90443f34ddd2fcc5012da84616c8af6040a01e91' 
  AND token = 'NbAGY2MHxoNGTtGvkTsLkjn6ubM2XlrRjH7C1imPREo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}