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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a18422a267755026d4017933c2b4a4080406700bf3d6ce27a59f06a609ae665' 
  AND token = 'Y1aT12HShxez+Z2fOTHK3kxr764s9UdMraUd/bkmUXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}