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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b6822ac297ee4775e7308120aed2eda1eab1fd510de74e89eba75d8ef815de1' 
  AND token = 'pDu7UVWpdmv21JHavhkGI4138U13SjTFGa/78d41O2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}