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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '797b78b4290667db97450c1e693ca88a02493602b572c46427953d3363d3cc53' 
  AND token = 'tWP/c67Am3dgB/rSvbgb+Qu5AR++P1A+fBp6vWp3XOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}