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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165e8844510d730544b50d9c8be2b638808a98d737a238423b38c962ed77bb6f' 
  AND token = 'rfWPAYRG1WEhwl4hY9wVatkR4It8hY8s7oXbSvnRgc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}