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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab548c36f5cbbf9c1fc7167556099d1d3aacc974f42e70b4c066e31784b5068' 
  AND token = 'sU8GO21ID+hOXDc+2qrPIye269AK+H1xMH63B+5zUo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}