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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8bc5f7cd347ee2fd6821778bc8dd66a6481048b158974e5f73c5a2d7fd4622df' 
  AND token = 'ktlzMm+up6nW+1Z4NogG2NU6ROrds0BQU3uVvvlC8vU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}