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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a77c9eacec2ed56873b02b5cbc19f6b0d92935df04506bd4d8298443b5c4ac53' 
  AND token = 'GjTgiGhQ2NfqFigvjGXSpEo5AaQEv4HsTDlM9SjbLCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}