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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cfb33ea7909e46ef925058128239b9078c27fb6a344769eee7ef2cb43b68aa0' 
  AND token = 'BZTcNMRp1hZNJYgApk/9cR5fwJkQe6PBplFQxW0jUcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}