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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708e272112be5a005016386b13e484003e4f47a8e67f067ea2a70a6e425985d8' 
  AND token = 'Mgq0KL64L62TJmca8Mh/lCsxy1Ydy3vDa3Fk8/vvxWM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}