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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4889b01a390ef5ba21dfff35e2f52709f6289ebfd2b4ac795a1be0b67d87c7b5' 
  AND token = '3CUelWbfef8wn2cNy/X8mu1Jgt+ANDPU4h2XHe6xIaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}