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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6ff4689ceafb79c01020833daf0d15a92c1b8c8cca4e5aab8c03e0fe0e96b2' 
  AND token = 'NLfN9A4afd9FTnUZKFuHcussrE9BylIWmiJqCIKPJmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}