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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5437b4ef3208b4d346e8bd11c971aa0112afc5914f70ef24960018b9e6e3e106' 
  AND token = 'ownYIW6bjDsdleOvW6KPen/CocFVTDwqRtU+8bMlY7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}