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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a65388d10430b4cda86a988c6d533984bd58a92a90b1800b973166e9187e962' 
  AND token = '3NpqxdYG+vxmW3e8lSAD/kHM9JkNvAm+OqdkVkYwTmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}