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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8225a30eaa84f3bbe415713a4a8d43d0d80ead3aaa45b8a0938b1895ba223976' 
  AND token = '+4d7kZMkYwzU1LNGqbp9UeERuiwzphvFIVCh837OBtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}