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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1a1ff93b3d1f43537d3e74d9b7f409e3183317c936637ac4205953395d1deed' 
  AND token = 'A0qoiY5C1B+xhKPEhkVwk66+q+8ScQuDwadaHdlVBhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}