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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cc1a54bc2965d820fbadc3ba07e553f7d81ff5e04098946d678fb40f14be08c' 
  AND token = 'khYJEJXymaiI57FnARBVGo9xam58dSczFBSQT5vjLBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}