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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6437fbca04c5e95d4543c62df8a4fefa1c7b3ddce737776ff2789080b075aba4' 
  AND token = 'T24Af4KZMQW6PcLsG8CnHqkwYt31Te2XZ3l9vOrTb8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}