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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7d16498c3b0b32cd706161c6bfae6aec9a61fa9afb903c147a4fbe288b33db2' 
  AND token = 'hXuHH4B9xWeNL3zot2C0KY2K8mqy1FcEzeTk1v0E5Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}