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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f8b4c12b93aebda04c4fa356c9bcb765cdadbb4c406a6ece7efbc58357973e' 
  AND token = 'aI0BXYn5F8pJt/8ZFEFoLjH3eIkhtLf8yngOz90cKxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}