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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bc4236782794c43668a257303b7157301af02aa4fddfa267728e48f1e9f83d1' 
  AND token = 'a2XF5eddgiJJWl/NedErgPFl/CUQ1hmw/Om5mSGxacM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}