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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7cdb74bb45a740bebc2b76a5654e3f26b7cc65be1b1ebae622b32548a7e59da' 
  AND token = 't6BgP8JtAD0iZb9moP0bMa9uMUd4H5o7TnSxMsdDjwo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}