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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46a145642ac4472a10d90f7a75dfa1abd22fe9a04ba049331b9e2176387f60e4' 
  AND token = 'JG/8WHqNjGpLLE/50o4RrCEeJA665F29gO4Ty50UEnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}