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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c18549069e084b2d52f16c2fc89b3a8f7d181bbb20d04eb1c4563ee84658d33' 
  AND token = 'XOfTtMP5PrOuWmQP19WhaDA9/6FO7+yR2wT3dfTtwVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}