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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcb98bf800e02285cf68b1789f7385eebe9b5b55fdfa3d2f91a22246b7aa18d1' 
  AND token = 'hmDcZCVTqAB4OSB4BhMJlRXD6pNV36BeioVHtymk45c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}