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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e569a8572fc82e41c23a035d7ff815c6bbbef2722eb69b6fc21f0be69ae17e9b' 
  AND token = 'Eamnmu+0Z4WI/ggReJn7mgHc2VGgC8wwUGVc0kdzSv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}