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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50f634172cc9be5023a3d9503005ce74b4f0402d104cb41290cfb9db1f3bbad' 
  AND token = 'yDWLEg6uRJJ3M+cexek7JV9iAHuoTOBV7wqV7HQ99M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}