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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8de933df83a6c6d83354482b3fd9e380e5418b45b363dac4ceb4ada1ffd878e' 
  AND token = 'Msahz4JKFJ7wVXNJTHUpXLchCI81bthO2IfGQa/m0DM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}