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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ddd73b6fbecdd6eb8e03a387602b6a18c5f70804bea2720e3879291ac7c218' 
  AND token = '0Txi4YEWPMh2uO2Mkp99ZC43pPI/O8ED4JlsJcnEBfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}