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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae31209e27bffb26fa872cea9eab4a250667ca65ab8489ae212a6e8f2d72b379' 
  AND token = 'QNv7bbtrijWCWR1nm8z2M+HjMoHkCrMqNpbrYccQG4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}