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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec63674729626c4b909eec36b3d51f5da4990fed3b6384bbd27640ae44ddc0e9' 
  AND token = 'acTSLS6g1p3WsI7BCslI+8wLQeuRCDeLxeneSye5PrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}