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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fa22d81c1012b3d56d33d9ec1202f0923f33a40a9a3ac2dcee36deec48e8928' 
  AND token = 'SXg72mhbn7qRZo2rv9aDpr+ueG7THCqJAPRfyxS2Gp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}