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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a51d7dfd0e710e2e2792c63c07c46bf300af3b1c9534a94e03d43021799a7c6' 
  AND token = 'PE4ykLECj3V9ka70o7ZUG+aOaTXScwqVulzU+nG+2/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}