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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd162ca2179a49b2bab9f98f79b7fdfd9830d25559122b428c3320a94eb9687c5' 
  AND token = 'UvXjLaTUDpl6fl4HdUEJTNAJsB7R9SrBBSBbNIMGjoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}