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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbe4a7f5ca1821108b8cba1649e3042c7a3ec2cab287f7ea21c1fb49990f8341' 
  AND token = 'SGyPtID7VlJgdCGNg2mt4CvvoaghOZGg14SuMXFhG6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}