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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28f19b82d7cee09c4be8b8931d743972c92a7e3e98d32918a0c51f1b90a54788' 
  AND token = 'BynvdMtm+R2Xo09Y7MDBdyWpRB5J5Tv3MH0uZIGtRak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}