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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f37d89e05b31ebc1f8021256f59865bae8790b60be832f59143ca28be1887b2a' 
  AND token = 'vny5ahFTrFUipemaGm1em623/HVBvgSpRlt8j/FStNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}