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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354a92bda651a67edef3140e400ab5c533356860f69e6c4366cd65d18dd7d34f' 
  AND token = 'd6J5c8AgN9uygnwi+G5jwyKhRKYodGoaq1YFo1ZBtqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}