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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65febc0b92b93dce143688706bcc8e76d4ac8a5e8dd45e152001cf8a19962f45' 
  AND token = '22XfxWGAHEAQnSBKyyZw+LeOnE7fFApVkhOp5MIUPUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}