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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40ab2e002df40be37ecafa730ec10340d25d59b3be5479a716d9a1c3bcc4468' 
  AND token = 's3O8XpChmYdEKszNwBAJjD8SDcKV3RKpcZ1ecpgdWLU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}