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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a0d39cac535c8807d73d9227454a1262d0f8189b3b1dae14e9481336d0dba59' 
  AND token = 'sEsfr9ysvg4hT1oEpW4ynJ/Py3HMejiw9RfrHS3WxEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}