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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7d0fff7a0c1c44e8b0d1158857c6a9166d303586540077e8f4457ecc610aa4f' 
  AND token = 'RuwFIg4AqBaj+DfVDX1eO7FfarPafpKtKDjlEZJLtTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}