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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6564911f3734b854c781041604d558b17d89c20b814f64c3b8a318d56f8623d' 
  AND token = 'LUnQdafEA0Gf3oy8mL3xWpBtv73aNgxbStvCh85y0Lo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}