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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0e750841637f51bdf7580371e4d1e8f8def60a0a17b4e5d1705c094a807c213' 
  AND token = 'BYf07pEK+TsdFBg6Kutxj8ZZo3UxjrXD07TIddbglqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}