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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '894f915ea494dd2ee4cb7ce10f28760904ac311c0e3b39c24431570f3c527723' 
  AND token = 'jIMPJB3CHEAqd5smmgM4Mqp3qHoLgvk9J+CEQwvDwz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}