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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04ae782d40a7e607c5edbefd3e55d9eda8be87e02d8292290416a2f3d89cb8e3' 
  AND token = '8+rWukRTIer2gAe6BeBPEg8I2cy5xNCMqHl7Pdj6HVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}