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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5625c351a2b3ab0e09fed1c3bf6f79a80989ae3fbc758a2bf13ec915981d72d0' 
  AND token = '3ez//O0dFJ+l7mkiaVRO2QQoibHmz5bG/Y1uJmXy1Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}