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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b409e90ac564088082b1aef6da32fef99b8425b75c1d800ab414c10c76d95cd1' 
  AND token = 'UR/hwN+1XQUZ2x1GcwBkdL9by4chMOjVORcTZ1JE7OQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}