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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41bd322144581c3036a5ca1bf08763f5b30fc61d120e91f82d2ebf0dd732ddd1' 
  AND token = '1JDUFR+2Thgy6PMx2BveTkL6YHpiujKwRS1kdtK0+BQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}