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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18a3f13fc8f5583362cf4093fe3042c933dae4e6de198148961ad668f1ad781a' 
  AND token = 'RD7Y++9vUJ4f68bQSMNsPmQNx5uQhzQnGbwfNheKaHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}